Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM50009248'
TargetFatty acid synthase(Homo sapiens (Human))
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of fatty acid synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN47VHPubMed
TargetFatty acid synthase(Homo sapiens (Human))
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of FAS in human ZR-75-1 cells by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0X86PubMed
TargetFatty acid synthase(Homo sapiens (Human))
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human FAS assessed as synthesis of long chain fatty acids from malonyl CoA after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3T5FPubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Yeungnam University

LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21WHWPubMed
TargetFatty acid synthase(Homo sapiens (Human))
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of FASMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NB7PubMed
TargetFatty acid synthase(Homo sapiens (Human))
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of FASN in human A375 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N8261PubMed