Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM50119581'
TargetFatty acid synthase(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50119581(CHEMBL3617742 | US10413545, Compound 23 | US971881...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of fatty acid synthase (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B334GPubMed
TargetFatty acid synthase(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50119581(CHEMBL3617742 | US10413545, Compound 23 | US971881...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of fatty acid synthase keto-reductase domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B334GPubMed
TargetFatty acid synthase(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50119581(CHEMBL3617742 | US10413545, Compound 23 | US971881...)copy SMILEScopy InChI
Affinity DataIC50: 56.2nMpH: 7.5 T: 2°CAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3PJBUS Patent
TargetFatty acid synthase(Homo sapiens (Human))
Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL
LigandPNGBDBM50119581(CHEMBL3617742 | US10413545, Compound 23 | US971881...)copy SMILEScopy InChI
Affinity DataIC50: 56.2nMAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H134CBUS Patent