Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1' and Ligand = 'BDBM391600'
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Genentech, Inc.

LigandPNGBDBM391600(ETI-T-255 | US10300048, Compound 2 | US10300048, E...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Screening for AEA cellular uptake inhibition was performed in a semi-automated procedure: Pipetting and washing steps were performed by a Biomek3000 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6F63US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Genentech, Inc.

LigandPNGBDBM391600(ETI-T-255 | US10300048, Compound 2 | US10300048, E...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Screening for AEA cellular uptake inhibition was performed in a semi-automated procedure: Pipetting and washing steps were performed by a Biomek3000 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6F63US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Genentech, Inc.

LigandPNGBDBM391600(ETI-T-255 | US10300048, Compound 2 | US10300048, E...)copy SMILEScopy InChI
Affinity DataIC50: 5.62E+4nMAssay Description:Hydrolysis of [3H]-AEA by FAAH was determined as previously described in cell homogenates of U937 cells (0.18 mg protein) (Omeir et al., 1999, Bioche...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6F63US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Genentech, Inc.

LigandPNGBDBM391600(ETI-T-255 | US10300048, Compound 2 | US10300048, E...)copy SMILEScopy InChI
Affinity DataIC50: 5.62E+4nMAssay Description:Hydrolysis of [3H]-AEA by FAAH was determined as previously described in cell homogenates of U937 cells (0.18 mg protein) (Omeir et al., 1999, Bioche...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6F63US Patent