Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM161389'
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161389(US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Purified recombinant human FGFR4 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161389(US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:The inhibitory effect of the compounds on FGFR4 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319ZZFUS Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161389(US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMMore data for this Ligand-Target Pair
In DepthDetails
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161389(US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human FGFR4 (445 to 753 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84GS6PubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161389(US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMMore data for this Ligand-Target Pair
In DepthDetails
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161389(US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43WXPubMed