Found 4 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM249428' TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Compounds were profiled for FGFR inhibition activity at Reaction Biology Corporation (Malvern, Pa.) with their Kinase HotSpot assay. See, Anastassiad...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 1nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) (Invitrogen™) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ I...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 1nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 μ...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 1nMAssay Description:Purified, recombinant FGFR4 was pre-incubated with 10 μM compound overnight at 4° C., or for 1 hour at room temperature. Following pre-incubatio...More data for this Ligand-Target Pair
