Found 12 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM50355393' TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:Recombinant FGFR1 (2.5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 μM, FGFR1 substrate); Pol...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 13nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) (Invitrogen™) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ I...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 13nMAssay Description:Recombinant FGFR1 (2.5 nM), or FGFR4 (12 nM) was prepared as a mixture with substrate KKKSPGEYVNIEFG (SEQ ID NO:1) (20 μM, FGFR1 substrate); Pol...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant FGFR4 (unknown origin) using peptidic substrates in presence of ATP by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant FGFR4More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 60nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEI...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
EISAI R&D MANAGEMENT CO., LTD.
US Patent
EISAI R&D MANAGEMENT CO., LTD.
US Patent
Affinity DataIC50: 168nMAssay Description:Inhibition of wild type FGFR4 expressed in HEK293 cells assessed as inhibition of autophosphorylation of tyrosine residue after 40 mins by ELISA assa...More data for this Ligand-Target Pair
Affinity DataIC50: 541nMAssay Description:Inhibition of FGFR4 in mouse BAF3 cells assessed as decrease in FGFR4 phosphorylation incubated for 40 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 581nMAssay Description:Inhibition of FGFR4 in mouse BAF3 cells assessed as reduction in cell viability incubated for 2 days by cell proliferation assayMore data for this Ligand-Target Pair
