Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Focal adhesion kinase 1' and Ligand = 'BDBM50430287'
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 5 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of intracellular FAK autophosphorylation in human PC3 M-luc cells after 2 hrsMore data for this Ligand-Target Pair