Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Folylpolyglutamate synthase, mitochondrial' and Ligand = 'BDBM50002472'
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002472(5-Amino-2-{4-[(2-amino-5-chloro-4-oxo-3,4-dihydro-...)copy SMILEScopy InChI
Affinity DataKi:  8.30nMAssay Description:Inhibitory activity of the compound against hog liver Folyl polyglutamate synthetase (FPGS)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26M35S6PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002472(5-Amino-2-{4-[(2-amino-5-chloro-4-oxo-3,4-dihydro-...)copy SMILEScopy InChI
Affinity DataKi:  8.30nMAssay Description:The apparent Km of compound as a substrate for partially purified mouse liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22806MJPubMed
TargetFolylpolyglutamate synthase, mitochondrial(Homo sapiens (Human))
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50002472(5-Amino-2-{4-[(2-amino-5-chloro-4-oxo-3,4-dihydro-...)copy SMILEScopy InChI
Affinity DataKi:  8.30E+3nMAssay Description:Compound was evaluated for its binding affinity against hog liver Folyl-polyglutamate synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X9297QPubMed