Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Free fatty acid receptor 1' and Ligand = 'BDBM50563855'
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50563855(CHEMBL4780641)copy SMILES
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-TAK-875 from human recombinant full-length GPR40 expressed in human HEK293 cell membrane incubated for 2 hrs by solid scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9NPCPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50563855(CHEMBL4780641)copy SMILES
Affinity DataKd:  9.5nMAssay Description:Displacement of [3H]-(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9NPCPubMed
TargetFree fatty acid receptor 1(Mus musculus)TBA
LigandPNGBDBM50563855(CHEMBL4780641)copy SMILES
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9NPCPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50563855(CHEMBL4780641)copy SMILES
Affinity DataEC50:  12nMAssay Description:Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9NPCPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50563855(CHEMBL4780641)copy SMILES
Affinity DataEC50:  55nMAssay Description:Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in intracellular calcium level measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9NPCPubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50563855(CHEMBL4780641)copy SMILES
Affinity DataEC50:  56nMAssay Description:Agonist activity at human recombinant full-length Prolink-tagged GPR40 fused with EA-tagged beta-arrestin expressed in human HEK293 cells assessed as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9NPCPubMed