Found 5 Enz. Inhib. hit(s) with Target = 'Free fatty acid receptor 2' and Ligand = 'BDBM50450263' TargetFree fatty acid receptor 2(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataKi: 204nMAssay Description:Displacement of [3H]-GLPG0974 from human FFA2 expressed in Flp-InT-REx 293 cell membranes after 2 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
3D Structure (crystal)TargetFree fatty acid receptor 2(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: 794nMAssay Description:Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.01E+3nMAssay Description:Agonist activity at FFA2R in mouse mature adipocytes assessed as inhibition of isoproterenol-induced glycerol productionMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: 78nMAssay Description:Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...More data for this Ligand-Target Pair
Affinity DataEC50: 363nMAssay Description:Agonist activity at mouse FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...More data for this Ligand-Target Pair
