Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'G-protein coupled bile acid receptor 1' and Ligand = 'BDBM50327537'
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327537(2-(4-bromophenyl)-N-((2-(thiophen-3-yl)quinolin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327537(2-(4-bromophenyl)-N-((2-(thiophen-3-yl)quinolin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed