Found 9 Enz. Inhib. hit(s) with Target = 'GABA-A receptor; alpha-5/beta-3/gamma-2' and Ligand = 'BDBM50065229' TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity measured using LtK- cell membranes expressing Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of [3H]-Ro-15-1788 binding to human GABA A receptor (alpha5-beta3-gamma2) stably expressed in L(tk-) cells.More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]- Ro 15-1788 binding from human GABA-A receptor alpha5-beta3-gamma2 subunitsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity to human GABA A alpha5-beta3-gamma2 receptor,using a [3H]-Ro- 15-1788 radioligandMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-5-beta-3-gamma-2 subunitsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]-Ro- 15-1788 from human gamma-aminobutyric-acid GABA-A receptor alpha5-beta3-gamma2 expressed in L(tk-) cells More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]-Ro- 15-1788 from human GABA-A alpha5-beta3-gamma2 receptor subunits expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University of Wisconsin-Milwaukee
Curated by ChEMBL
University of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Binding affinity to human alpha5beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
