Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [489-587]' and Ligand = 'BDBM50005687'
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research Canada

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzyme (by Dixon analysis)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959T5PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research Canada

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured (exp 2)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2057DWMPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research Canada

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959T5PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research Canada

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measuredMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2057DWMPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research Canada

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzymeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959T5PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research Canada

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Binding affinity against HIV Protease enzyme.(by Dixon analysis)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959T5PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research Canada

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzyme.(value reported by Roche group)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959T5PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research Canada

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Binding activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B858Q3PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research Canada

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Binding activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B858Q3PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Syntex Research Canada

Curated by ChEMBL
LigandPNGBDBM50005687(1-[3-(2-Benzyloxycarbonylamino-3-carbamoyl-propion...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzyme.(value reported by Roche group)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W959T5PubMed