BindingDB PrimarySearch

Found 1 Enz. Inhib. hit(s) with Target = 'Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2' and Ligand = 'BDBM50157981'

Gamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL

BDBM50157981(5-Chloro-thiophene-2-sulfonic acid {5-[2-(2-methyl...)copy SMILEScopy InChI

IC50: 335nMAssay Description:Inhibitory concentration against Gamma-secretase in whole cell inhibition assay using SH-SY5Y cellsMore data for this Ligand-Target Pair

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UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2445KZQPubMed