Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50007435'
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007435(CHEMBL3237915)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Displacement of [125I]-glucagon from recombinant human GCGR expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8F9PPubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007435(CHEMBL3237915)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-stimulated cAMP production preincubated for 30 mins follo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8F9PPubMed
TargetGlucagon receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007435(CHEMBL3237915)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8F9PPubMed