Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM13775'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM13775((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Displacement of [3H]DEX from human glucocorticoid receptorMore data for this Ligand-Target Pair
LigandPNGBDBM13775((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with CCL2-promoter luciferase plasmid construct assessed as reducti...More data for this Ligand-Target Pair
LigandPNGBDBM13775((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 316nMMore data for this Ligand-Target Pair
LigandPNGBDBM13775((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)copy SMILEScopy InChI
Affinity DataEC50:  100nMMore data for this Ligand-Target Pair
LigandPNGBDBM13775((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)copy SMILEScopy InChI
Affinity DataEC50:  2.51E+3nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM13775((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)copy SMILEScopy InChI
Affinity DataKd:  43nMAssay Description:Displacement of 1 x 10'-8 M of [1,2,3-3H]-triamcinolone acetonide from glucocorticoid receptor in soluble fraction of mouse L929 cells after 20 hrsMore data for this Ligand-Target Pair