Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM19205'
LigandPNGBDBM19205((1R)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...)copy SMILEScopy InChI
Affinity DataIC50: 0.251nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with CCL2-promoter luciferase plasmid construct assessed as reducti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4H3NPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM19205((1R)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...)copy SMILEScopy InChI
Affinity DataIC50: 77.3nMpH: 7.5 T: 2°CAssay Description:The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BKZPubMed
LigandPNGBDBM19205((1R)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...)copy SMILEScopy InChI
Affinity DataEC50:  794nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4H3NPubMed