Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50110730'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Eli Lilly Biotechnology Center

Curated by ChEMBL
LigandPNGBDBM50110730(CHEMBL3605919)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Eli Lilly Biotechnology Center

Curated by ChEMBL
LigandPNGBDBM50110730(CHEMBL3605919)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity against glucocorticoid receptor (unknown origin) expressed in HEK293 cells by GRE-dependent luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(RAT)
Eli Lilly Biotechnology Center

Curated by ChEMBL
LigandPNGBDBM50110730(CHEMBL3605919)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Antagonist activity against glucocorticoid receptor in rat H4-IIE cells assessed as inhibition of dexamethasone-induced receptor transactivation pre-...More data for this Ligand-Target Pair