Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50326953'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50326953(1,1,1-Trifluoro-4-(3-fluorophenyl)-4-methyl-2-(1H-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Binding affinity to glucocorticoid receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled Dexamethasone by fluore...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571D0XPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50326953(1,1,1-Trifluoro-4-(3-fluorophenyl)-4-methyl-2-(1H-...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Transrepression activity at glucocorticoid receptor in HFF assessed as inhibition of IL-1-induced IL-6 production after 18 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571D0XPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50326953(1,1,1-Trifluoro-4-(3-fluorophenyl)-4-methyl-2-(1H-...)copy SMILEScopy InChI
Affinity DataEC50: >2.00E+3nMAssay Description:Transactivation activity at glucocorticoid receptor in HFF assessed as induction of aromatase activity after 18 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571D0XPubMed