Found 4 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50326958' TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Binding affinity to glucocorticoid receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled Dexamethasone by fluore...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Transrepression activity at glucocorticoid receptor in HFF assessed as inhibition of IL-1-induced IL-6 production after 18 to 24 hrs by ELISAMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Transactivation activity at glucocorticoid receptor in human HeLa cells transfected with luciferase gene linked to MMTV promoter by luciferase assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Boehringer-Ingelheim Pharmaceuticals Inc.
Curated by ChEMBL
Affinity DataEC50: 45nMAssay Description:Transactivation activity at glucocorticoid receptor in HFF assessed as induction of aromatase activity after 18 to 24 hrs by ELISAMore data for this Ligand-Target Pair
