Found 3 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50411044' TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 501nMAssay Description:Activity at GR assessed as ability to antagonize dexamethasone-induced MMTV luciferase reporter gene transactivation in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
