TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataEC50: <1.00E+4nMAssay Description:Agonist activity at GR assessed as MMTV-mediated transactivation of renilla luciferase gene in human A549 cells relative to DexamethasoneChecked by AuthorMore data for this Ligand-Target Pair
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