Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50415790'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50415790(CHEMBL1093774 | GSK-1564023A | US10272074, Example...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2XDJPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50415790(CHEMBL1093774 | GSK-1564023A | US10272074, Example...)copy SMILEScopy InChI
Affinity DataIC50: 275nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P33Z7US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50415790(CHEMBL1093774 | GSK-1564023A | US10272074, Example...)copy SMILEScopy InChI
Affinity DataEC50: >6.31E+3nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as renilla luciferase transactivation activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2XDJPubMed