Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Glutamate receptor 4' and Ligand = 'BDBM50002369'
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly and Company Ltd

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)copy SMILEScopy InChI
Affinity DataKi:  1.71E+3nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 4 using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly and Company Ltd

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)copy SMILEScopy InChI
Affinity DataKi:  1.71E+3nMAssay Description:Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly and Company Ltd

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)copy SMILEScopy InChI
Affinity DataKi:  1.71E+3nMAssay Description:Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 4 in HEK293 cells using [3H]-AMPA as radioligandMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre for Drug Discovery and Development (NatSynDrugs)

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)copy SMILEScopy InChI
Affinity DataKi:  3.57E+3nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR4 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre for Drug Discovery and Development (NatSynDrugs)

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)copy SMILEScopy InChI
Affinity DataEC50:  4.70E+4nMAssay Description:Agonist activity at rat recombinant GluR4 flip isomer expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assa...Checked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre for Drug Discovery and Development (NatSynDrugs)

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)copy SMILEScopy InChI
Affinity DataEC50:  4.70E+4nMAssay Description:Agonist activity at rat recombinant GluA4 receptor flip isoform expressed in HEK293 cells assessed as effect on cyclothiazide-induced calcium flux by...More data for this Ligand-Target Pair