Found 4 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, kainate 1' and Ligand = 'BDBM50207594' TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Centro de Investigación Lilly
Curated by ChEMBL
Centro de Investigación Lilly
Curated by ChEMBL
Affinity DataKi: 1.17E+4nMAssay Description:Inhibition of [3H]-KA binding to iontropic glutamate receptor 5More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Centro de Investigación Lilly
Curated by ChEMBL
Centro de Investigación Lilly
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Antagonist activity at human recombinant GLUK5 receptor expressed in HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx by FL...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Centro de Investigación Lilly
Curated by ChEMBL
Centro de Investigación Lilly
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUK5 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.78E+3nMAssay Description:Antagonism on GLUK5 containing kainate induced deploarization of isolated neonatal rat dorsal root C-fibersMore data for this Ligand-Target Pair
