Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial' and Ligand = 'BDBM404912'
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404912((S)-1-(2-fluoro-4-(6-(2-(pyridin-2- yl)acetamido)p...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404912((S)-1-(2-fluoro-4-(6-(2-(pyridin-2- yl)acetamido)p...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20Z76GPUS Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404912((S)-1-(2-fluoro-4-(6-(2-(pyridin-2- yl)acetamido)p...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765HQCUS Patent