Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM13533'
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC61NHPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human GSK-3beta using Ser/Thr 6 peptide as substrate preincubated for 60 mins followed by ATP and substrate addition and measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HMMPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of UmGSK3 by kinase inhibitors.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1PNHPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Ansaris

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for full-length GSK3BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed