Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM7263'
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

LigandPNGBDBM7263(9-cyanopaullone | 9-oxo-8,18-diazatetracyclo[9.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 10nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM7263(9-cyanopaullone | 9-oxo-8,18-diazatetracyclo[9.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of GSK3beta (unknown origin) expressed in Sf9 cells using GS1 as substrate and [gamma32]ATP after 30 min by scinitllation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319ZRR
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM7263(9-cyanopaullone | 9-oxo-8,18-diazatetracyclo[9.7.0...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of GSK3-beta expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C1VPubMed