BindingDB PrimarySearch

Found 2 Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM7304'

Glycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£t Braunschweig

Curated by ChEMBL

BDBM7304(14-bromo-18-(prop-2-en-1-yl)-8,18-diazatetracyclo[...)copy SMILEScopy InChI

IC50: 4.00E+3nMAssay Description:Inhibition of GSK3-beta expressed in insect Sf9 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q26W9C1VPubMed

Glycogen synthase kinase-3 beta(Rattus norvegicus (rat))
CNRS

BDBM7304(14-bromo-18-(prop-2-en-1-yl)-8,18-diazatetracyclo[...)copy SMILEScopy InChI

IC50: 4.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2CR5RJSPubMed