Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Glycylpeptide N-tetradecanoyltransferase 1/2' and Ligand = 'BDBM50101969'
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50101969(3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against Candida albicans N-myristoyltransferase (CaNmt)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KS6TRWPubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50101969(3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC34K1PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50101969(3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+5nMAssay Description:Inhibitory activity against human N-Myristoyltransferase (HsNmt) assessed as inhibitory concentration using substrate peptide and myristotyl-CoA at 0...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC34K1PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50101969(3-Methyl-4-{3-[(pyridin-3-ylmethyl)-amino]-propoxy...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+5nMAssay Description:In vitro ability of the compound to displace radiolabelled FTI from farnesyltransferase in cultured Ha-ras transformed RAT1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KS6TRWPubMed