Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50244176'
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244176(5-({4-[2-(4-tert-Butylphenyl)-1H-benzimidazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244176(5-({4-[2-(4-tert-Butylphenyl)-1H-benzimidazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244176(5-({4-[2-(4-tert-Butylphenyl)-1H-benzimidazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244176(5-({4-[2-(4-tert-Butylphenyl)-1H-benzimidazol-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Antagonist activity at recombinant GnRH receptor in CO2 asphyxiated rat primary pituitary cells assessed as reduction in (D-Trp6)LHRH-induced LH rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed