Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha/90-beta' and Ligand = 'BDBM50486032'
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486032(CHEMBL2204497)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
LigandPNGBDBM50486032(CHEMBL2204497)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of Hsp90 in human NCI-N87 cells assessed as Her2 degradation after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M68KKPubMed