Found 2 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha' and Ligand = 'BDBM126017'
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.
Curated by ChEMBL
Taiho Pharmaceutical Co. Ltd.
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Displacement of biotin-labeled geldanamycin from His-tagged HSP90alpha NTD (unknown origin) preincubated for 2 hrs followed by biotin-labeled geldana...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Taiho Pharmaceutical Co. Ltd.
Curated by ChEMBL
Taiho Pharmaceutical Co. Ltd.
Curated by ChEMBL
Affinity DataIC50: 160nMpH: 7.5Assay Description:The HSP90-binding activity was measured by an AlphaScreen competitive assay system. The purified HSP90 solution was diluted with a binding buffer (50...More data for this Ligand-Target Pair