Found 2 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-beta' and Ligand = 'BDBM50357454' TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development
Curated by ChEMBL
Sanofi-Aventis Research and Development
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
3D Structure (crystal)TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development
Curated by ChEMBL
Sanofi-Aventis Research and Development
Curated by ChEMBL
Affinity DataKd: 0.350nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
