Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM24470'
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24470(7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. Mole...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24470(7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant c-Met kinase domain (unknown origin) incubated for 30 mins using gastrin peptide substrate by HTRF assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24470(7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24470(7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...)copy SMILEScopy InChI
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24470(7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24470(7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24470(7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of HGF-mediated human c-Met autophosphorylation expressed in human PC3 cells after 1 hr by electrochemiluminescent immunoassayMore data for this Ligand-Target Pair