Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM24475'
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24475(4-{[6-(3,5-difluorophenyl)-[1,2,4]triazolo[4,3-a]p...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. Mole...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P2ZZ6PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24475(4-{[6-(3,5-difluorophenyl)-[1,2,4]triazolo[4,3-a]p...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2891676PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24475(4-{[6-(3,5-difluorophenyl)-[1,2,4]triazolo[4,3-a]p...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JZHPubMed