Found 7 Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM226354' 
Affinity DataIC50: 4nMAssay Description:Antagonist activity at unphosphorylated human His-tagged TrkA (441 to 796 residues) expressed in baculovirus expression system preincubated for 20 mi...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 6nMAssay Description:Antagonist activity at unphosphorylated rat TrkA expressed in baculovirus expression system preincubated for 20 mins followed by TK-substrate-Biotin ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at prolink-tagged TrkA (unknown origin) expressed in cells assessed as inhibition of NGF-induced receptor phosphorylation by meas...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Antagonist activity at TrkA in rat DRG assessed as inhibition of NGF-induced ERK phosphorylation preincubated for 60 mins followed by NGF addition an...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Antagonist activity at phosphorylated human His-tagged TrkA (441 to 796 residues) expressed in baculovirus expression system preincubated for 20 mins...More data for this Ligand-Target Pair
Affinity DataKd: 4.20nMAssay Description:Binding affinity to C-terminal-His6/N-terminal BAP-tagged unphosphorylated TrkA (unknown origin) (441 to 796 residues) by SPR analysisMore data for this Ligand-Target Pair
