Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM50457833'
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50457833(CHEMBL4210892)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at prolink-tagged TrkA in human U2OS cells assessed as inhibition of beta-NGF-induced receptor phosphorylation by measuring reduc...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50457833(CHEMBL4210892)copy SMILEScopy InChI
Affinity DataKd:  4.70nMAssay Description:Binding affinity to un phosphorylated C-terminal His6/N-terminal BAP-tagged TrkA (441 to 796 residues) (unknown origin) assessed as dissociation rate...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50457833(CHEMBL4210892)copy SMILEScopy InChI
Affinity DataKd:  0.700nMAssay Description:Binding affinity to un phosphorylated C-terminal His6/N-terminal BAP-tagged TrkA (441 to 796 residues) (unknown origin) by SPR assayMore data for this Ligand-Target Pair