Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Histone acetyltransferase p300' and Ligand = 'BDBM50542052'
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50542052(CHEMBL4643833 | US11274090, Example 152 Isomer 2)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Binding affinity to recombinant N-terminal His-tagged EP300 HAT domain (unknown origin) (1287 to 1666 residues) expressed in Escherichia coli incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NT5PubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50542052(CHEMBL4643833 | US11274090, Example 152 Isomer 2)copy SMILEScopy InChI
Affinity DataIC50: 31.8nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C53Q11US Patent