Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Histone deacetylase' and Ligand = 'BDBM25150'
TargetHistone deacetylase(Homo sapiens (Human))
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC in human HeLa cell extractsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8WGCPubMed
TargetHistone deacetylase(Homo sapiens (Human))
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of HDAC in human HeLa cells nuclear extracts incubated for 30 mins by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GQQPubMed
TargetHistone deacetylase(Homo sapiens (Human))
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of HDAC in human HeLa cells using Fluor de Lys as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0C7PPubMed
TargetHistone deacetylase(Homo sapiens (Human))
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PCJPubMed
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Dipartimento di Chimica e Tecnologie del Farmaco "Sapienza" Universit£ di Roma

Curated by ChEMBL
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataIC50: 215nMAssay Description:Inhibition of HDAC1 in Plasmodium falciparum 3D7 nuclear extract using Ac-RGK(Ac)-AMC fluorogenic peptide as substrate preincubated for 1 hr followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD50D0PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Hunan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)copy SMILEScopy InChI
Affinity DataEC50:  30nMAssay Description:Inhibition of HDAC in human cell lysates using fluoro-substrate peptide/fluoro-deacetylated peptide as substrate incubated for 20 mins measured at 1 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75K03PubMed