Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM417063'
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM417063(4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of full length recombinant C-terminal FLAG-His-tagged human HDAC1 expressed in baculovirus infected Sf21 insect cells using RHK-K(Ac)-AMC ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222ZJFPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM417063(4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 5.23E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD15N3PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM417063(4-((3,4-dihydroquinolin-1(2H)-yl)methyl)-N-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.11E+4nMAssay Description:The effectiveness, or potency, of a present HDACI with respect to inhibiting the activity of an HDAC is measured by an IC50 value. The quantitative I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q81GFWUS Patent