Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50248522'
TargetHistone deacetylase 1(Homo sapiens (Human))
S*BIO Pte Ltd.

Curated by ChEMBL
LigandPNGBDBM50248522(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Competitive inhibition of HDAC1 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RD6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*BIO Pte Ltd.

Curated by ChEMBL
LigandPNGBDBM50248522(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of full length recombinant HDAC1 using Fluor de Lys as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RD6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*BIO Pte Ltd.

Curated by ChEMBL
LigandPNGBDBM50248522(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8KX3PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*BIO Pte Ltd.

Curated by ChEMBL
LigandPNGBDBM50248522(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ64P8US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
S*BIO Pte Ltd.

Curated by ChEMBL
LigandPNGBDBM50248522(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0J7FUS Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
S*BIO Pte Ltd.

Curated by ChEMBL
LigandPNGBDBM50248522(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN98P2US Patent