Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50276074'
TargetHistone deacetylase 1(Homo sapiens (Human))
Genentech, Inc.

LigandPNGBDBM50276074(CHEMBL470791 | HDAC inhibitor, Compound 2 | N-(2-a...)copy SMILEScopy InChI
Affinity DataIC50: 7.93nMpH: 7.5Assay Description:Biochemical assays of HDAC activity were carried out by Nanosyn in a reaction volume of 10 ul in 384-well microplates. A standard enzymatic reaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK99MZPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Genentech, Inc.

LigandPNGBDBM50276074(CHEMBL470791 | HDAC inhibitor, Compound 2 | N-(2-a...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human HDAC1 expressed in mammalian cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SQ2PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Genentech, Inc.

LigandPNGBDBM50276074(CHEMBL470791 | HDAC inhibitor, Compound 2 | N-(2-a...)copy SMILEScopy InChI
Affinity DataKd:  24.6nMpH: 8.0Assay Description:Specifically, the experiments were conducted in black 384-well polypropylene plates (Corning Glass) in a 15-ul reaction volume consisting of 11 nM HD...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK99MZPubMed