Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50555460'
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50555460(CHEMBL4785064)copy SMILES
Affinity DataIC50: 0.850nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate measured after 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765K0SPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50555460(CHEMBL4785064)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765K0SPubMed