Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 2' and Ligand = 'BDBM178100'
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute of Harvard and MIT

LigandPNGBDBM178100(BRD3308 | US11377423, Cmpd 1)copy SMILEScopy InChI
Affinity DataKi:  6.30E+3nM ΔG°:  -29.7kJ/mole IC50: 1.15E+3nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64T2PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute of Harvard and MIT

LigandPNGBDBM178100(BRD3308 | US11377423, Cmpd 1)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human HDAC2 expressed in Sf9 cells using carboxyfluorescein (FAM)-labeled acetylated peptide substrate preincubated for 3 hrs by microf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute of Harvard and MIT

LigandPNGBDBM178100(BRD3308 | US11377423, Cmpd 1)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute of Harvard and MIT

LigandPNGBDBM178100(BRD3308 | US11377423, Cmpd 1)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC2 expressed in Sf9 insect cells using FAM-labeled acetylated peptide A as subs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93BZTPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute of Harvard and MIT

LigandPNGBDBM178100(BRD3308 | US11377423, Cmpd 1)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7DPJUS Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute of Harvard and MIT

LigandPNGBDBM178100(BRD3308 | US11377423, Cmpd 1)copy SMILEScopy InChI
Affinity DataIC50: 1.42E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7DPJUS Patent