Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 3' and Ligand = 'BDBM25159'
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of HDAC3 purified from HEK293 cells by western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987XHPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM/Merck

LigandPNGBDBM25159(CHEMBL462208 | N-[(1S)-1-phenylethyl]-5-(2,2,2-tri...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X6GPubMed