Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 3' and Ligand = 'BDBM25163'
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM25163(CHEMBL497332 | N-methyl-N-(quinoxalin-6-ylmethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:Inhibition of HDAC3 purified from HEK293 cells by western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987XHPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
IRBM-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM25163(CHEMBL497332 | N-methyl-N-(quinoxalin-6-ylmethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 670nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3R28PubMed