Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 4' and Ligand = 'BDBM50207561'
TargetHistone deacetylase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys (trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X352B7PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of HDAC4 catalytic domain (648 to 1057 residues) (unknown origin) using Boc-Lys-TFA as substrate measured after 60 mins by fluorescence as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44TJZPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC4 (612-1034) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ87QHPubMed