Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM50207561'
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Queensland

LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMpH: 8.0Assay Description:Fluorescence readings were carried out on a CytofluorR Series 4000 fluorescence multiwell plate reader (Perspective Biosystems). Stock solutions of t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9P97PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Queensland

LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged HDAC6 (438-915) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ87QHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Queensland

LigandPNGBDBM50207561(CHEMBL396097 | Class IIa HDAC inhibitor, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human HDAC6 expressed in HEK293 cells using Lys-Ac-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44TJZPubMed