Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM50354086'
TargetHistone deacetylase 8(Homo sapiens (Human))
Ronzoni Institute for Chemical and Biochem. Research

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of HDAC8 (unknown origin) incubated for 1 hr by fluor de lys substrate based fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N82XFPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Ronzoni Institute for Chemical and Biochem. Research

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6T01PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Ronzoni Institute for Chemical and Biochem. Research

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate by two-step fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2HJ9PubMed